Tet1 Suppresses p21 to Ensure Proper Cell Cycle Progression in Embryonic Stem Cells
Ten eleven translocation 1 (Tet1) is a DNA dioxygenase that promotes DNA demethylation by oxidizing 5-methylcytosine. It can also partner with chromatin-activating and repressive complexes to regulate gene expressions independent of its enzymatic activity. Tet1 is highly expressed in embryonic stem...
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2022-04-01
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| Schriftenreihe: | Cells |
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| Online-Zugang: | https://www.mdpi.com/2073-4409/11/8/1366 |
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