Beyond Genes: Inclusion of Alternative Splicing and Alternative Polyadenylation to Assess the Genetic Architecture of Predisposition to Voluntary Alcohol Consumption in Brain of the HXB/BXH Recombinant Inbred Rat Panel

Post transcriptional modifications of RNA are powerful mechanisms by which eukaryotes expand their genetic diversity. For instance, researchers estimate that most transcripts in humans undergo alternative splicing and alternative polyadenylation. These splicing events produce distinct RNA molecules,...

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Үндсэн зохиолчид:	Ryan Lusk, Paula L. Hoffman, Spencer Mahaffey, Samuel Rosean, Harry Smith, Jan Silhavy, Michal Pravenec, Boris Tabakoff, Laura M. Saba
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2022-03-01
Цуврал:	Frontiers in Genetics
Нөхцлүүд:	HXB/BXH recombinant inbred panel voluntary alcohol consumption transcriptome weighted gene co expression network analysis alternative splicing alternative polyadenylation
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fgene.2022.821026/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!