Sirolimus treatment for intractable lymphatic anomalies: an open-label, single-arm, multicenter, prospective trial

IntroductionIntractable lymphatic anomalies (LAs) include cystic lymphatic malformation (LM; macrocystic, microcystic, or mixed), generalized lymphatic anomaly, and Gorham–Stout disease. LAs can present with severe symptoms and poor prognosis. Thus, prospective studies for treatments are warranted....

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Autors principals:	Michio Ozeki, Saori Endo, Shiho Yasue, Akifumi Nozawa, Ryuta Asada, Akiko M. Saito, Hiroya Hashimoto, Takumi Fujimura, Yohei Yamada, Tatsuo Kuroda, Shigeru Ueno, Shoji Watanabe, Shunsuke Nosaka, Mikiko Miyasaka, Akihiro Umezawa, Kentaro Matsuoka, Takanobu Maekawa, Satoshi Hirakawa, Taizo Furukawa, Shigehisa Fumino, Tatsuro Tajiri, Junkichi Takemoto, Ryota Souzaki, Yoshiaki Kinoshita, Akihiro Fujino
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-02-01
Col·lecció:	Frontiers in Medicine
Matèries:	lymphatic anomalies lymphatic malformation generalized lymphatic anomaly Gorham–stout disease mammalian target of rapamycin
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fmed.2024.1335469/full
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