Arylaminopropanone Derivatives as Potential Cholinesterase Inhibitors: Synthesis, Docking Study and Biological Evaluation

Neurodegenerative diseases in which the decrease of the acetylcholine is observed are growing worldwide. In the present study, a series of new arylaminopropanone derivatives with <i>N</i>-phenylcarbamate moiety (<b>1–16</b>) were prepared as potential acetylcholinesterase and butyrylcholinesterase i...

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Autors principals:	Anna Hudcová, Aleš Kroutil, Renata Kubínová, Adriana D. Garro, Lucas J. Gutierrez, Daniel Enriz, Michal Oravec, Jozef Csöllei
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2020-04-01
Col·lecció:	Molecules
Matèries:	arylaminopropanone <i>N</i>-phenylcarbamate acetylcholinesterase butyrylcholinesterase enzyme assays molecular modelling
Accés en línia:	https://www.mdpi.com/1420-3049/25/7/1751
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