Arylaminopropanone Derivatives as Potential Cholinesterase Inhibitors: Synthesis, Docking Study and Biological Evaluation

Neurodegenerative diseases in which the decrease of the acetylcholine is observed are growing worldwide. In the present study, a series of new arylaminopropanone derivatives with <i>N</i>-phenylcarbamate moiety (<b>1–16</b>) were prepared as potential acetylcholinesterase and butyrylcholinesterase i...

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Hlavní autoři:	Anna Hudcová, Aleš Kroutil, Renata Kubínová, Adriana D. Garro, Lucas J. Gutierrez, Daniel Enriz, Michal Oravec, Jozef Csöllei
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2020-04-01
Edice:	Molecules
Témata:	arylaminopropanone <i>N</i>-phenylcarbamate acetylcholinesterase butyrylcholinesterase enzyme assays molecular modelling
On-line přístup:	https://www.mdpi.com/1420-3049/25/7/1751
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