Simulation study for evaluating an adaptive-randomisation Bayesian hybrid trial design with enrichment

Background: As we enter the era of precision medicine, the role of adaptive designs, such as response-adaptive randomisation or enrichment designs in drug discovery and development, has become increasingly important to identify the treatment given to a patient based on one or more biomarkers. Tailor...

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Autors principals:	Valentin Vinnat, Jean-Daniel Chiche, Alexandre Demoule, Sylvie Chevret
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2023-06-01
Col·lecció:	Contemporary Clinical Trials Communications
Matèries:	Response-adaptive randomisation Marker-based strategy designs Bayesian designs Precision medicine
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S245186542300087X
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