DNA G-Quadruplexes as Targets for Natural Product Drug Discovery
DNA guanine (G)-quadruplexes (G4s) are unique secondary structures formed by two or more stacked G-tetrads in G-rich DNA sequences. These structures have been found to play a crucial role in highly transcribed genes, especially in cancer-related oncogenes, making them attractive targets for cancer t...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2024-07-01
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| Edice: | Engineering |
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| On-line přístup: | http://www.sciencedirect.com/science/article/pii/S2095809924002467 |
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