O-GlcNAc transferase OGT-1 and the ubiquitin ligase EEL-1 modulate seizure susceptibility in C. elegans

Neurodevelopmental disorders such as epilepsy and autism have been linked to an imbalance of excitation and inhibition (E/I) in the central nervous system. The simplicity and tractability of C. elegans allows our electroconvulsive seizure (ES) assay to be used as a behavioral readout of the locomoto...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Nirthieca Suthakaran, Jonathan Wiggins, Andrew Giles, Karla J. Opperman, Brock Grill, Ken Dawson-Scully
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2021-01-01
coleção:	PLoS ONE
Acesso em linha:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604358/?tool=EBI
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!