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Targeting senescent microglia in progressive multiple sclerosis: a geroscience-informed approach

Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disorder of the central nervous system (CNS). Age is the strongest predictor of disease phenotype, with the majority of older adults transitioning to a progressive form marked by irreversible neurological decline. This clinical pro...

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Hlavní autoři: Jeffrey Atkinson, Amy Dokiburra, Hayley Groover, Jonathan P. Godbout, Benjamin M. Segal, Yinan Zhang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2025-10-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1681724/full
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