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Targeting senescent microglia in progressive multiple sclerosis: a geroscience-informed approach

Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disorder of the central nervous system (CNS). Age is the strongest predictor of disease phenotype, with the majority of older adults transitioning to a progressive form marked by irreversible neurological decline. This clinical pro...

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Bibliografiske detaljer
Principais autores: Jeffrey Atkinson, Amy Dokiburra, Hayley Groover, Jonathan P. Godbout, Benjamin M. Segal, Yinan Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-10-01
Serier:Frontiers in Immunology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1681724/full
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