Dearomatization of 3-Aminophenols for Synthesis of Spiro[chromane-3,1′-cyclohexane]-2′,4′-dien-6′-ones via Hydride Transfer Strategy-Enabled [5+1] Annulations

The Sc(OTf)₃-catalyzed dearomative [5+1] annulations between readily available 3-aminophenols and <i>O</i>-alkyl <i>ortho</i>-oxybenzaldehydes were developed for synthesis of spiro[chromane-3,1′-cyclohexane]-2′,4′-dien-6′-ones. The “two-birds-with-one-stone” strategy was disclosed by the...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Jia-Cheng Ge, Yufeng Wang, Feng-Wei Guo, Xiangyun Kong, Fangzhi Hu, Shuai-Shuai Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-02-01
Serie:	Molecules
Soggetti:	dearomatization spiro[chromane-3,1′-cyclohexane]-2′,4′-dien-6′-ones C(sp<sup>3</sup>)–H bond functionalization antifungal activity
Accesso online:	https://www.mdpi.com/1420-3049/29/5/1012
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!