Cytoplasmic localization of pseudouridine synthase 7 facilitates a pseudouridine-dependent enhancement of cellular stress tolerance

Abstract Pseudouridine (Ψ) is an abundant post-transcriptional modification found across all classes of RNA. It is widely speculated that Ψ inclusion in messenger RNAs (mRNAs) might provide an avenue for cells to control gene expression post-transcriptionally. Here we demonstrate that one of the pri...

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Auteurs principaux:	Minli Ruan, Sean M. Engels, Matthew R. Burroughs, Xiaoyan Li, Rosella Stower, Talia Tzadikario, Connor Powell, Dylan Bloch, Oleksandra Fanari, Stuart Akeson, Daniel E. Eyler, Chase A. Weidmann, Sara Rouhanifard, Miten Jain, Lydia M. Contreras, Kristin S. Koutmou
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2026-04-01
Collection:	Nature Communications
Accès en ligne:	https://doi.org/10.1038/s41467-026-71654-y
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