Multi-drug pharmacotyping improves therapy prediction in pancreatic cancer organoids

Abstract Patient-Derived Organoids (PDOs) represent a promising technology for therapy prediction in pancreatic cancer, with the potential of enhancing treatment outcomes and allowing more effective, personalized treatment choices. However, classification approaches into sensitive and resistant mode...

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Bibliografiske detaljer

Principais autores:	Katharina Wansch, Uwe Pelzer, François Schneider, Florian Dölvers, Anna Kühn, Mihnea P. Dragomir, Jana Ihlow, Georg Hilfenhaus, Loredana Vecchione, Matthäus Felsenstein, Dou Ma, Markus Lerchbaumer, Christian Jürgensen, Marcus Bahra, Adrian E. Granada, Gregor Duwe, Sebastian Stintzing, Ulrich Keilholz, Christopher C. M. Neumann
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2025-09-01
Serier:	Cancer Cell International
Fag:	Pancreatic adenocarcinoma Patient-derived organoids Multi-Drug response metrics Pharmacokinetic modelling
Online adgang:	https://doi.org/10.1186/s12935-025-03969-7
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