Amyloid β induces interneuron-specific changes in the hippocampus of APPNL-F mice.
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and amyloid-beta (Aβ) depositions generated by the proteolysis of amyloid precursor protein (APP) in the brain. In APPNL-F mice, APP gene was humanized and contains two familial AD mutations, and APP-unlike o...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2020-01-01
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| Serie: | PLoS ONE |
| Accesso online: | https://doi.org/10.1371/journal.pone.0233700 |
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