Divergent regulation of cellular cholesterol metabolism by seaweed-derived fucosterol and saringosterol

Marine sterols from brown seaweeds, particularly fucosterol and its oxidized derivative saringosterol, have shown therapeutic potential for Alzheimer’s disease (AD) and cardiovascular diseases. Here, we aimed to elucidate the cellular and in vivo mechanisms underlying their beneficial effects. In hu...

Полное описание

Библиографические подробности

Главные авторы:	Na Zhan, Nikita Martens, Yanlin Li, Gardi Voortman, Frank Leijten, Silvia Friedrichs, Martien P. M. Caspers, Lars Verschuren, Tim Vanmierlo, Marieke Smit, Folkert Kuipers, Johan W. Jonker, Vincent W. Bloks, Marcella Palumbo, Francesca Zimetti, Maria Pia Adorni, Hongbing Liu, Dieter Lütjohann, Monique T. Mulder
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2025-12-01
Серии:	Frontiers in Marine Science
Предметы:	fucosterol saringosterol liver X receptors cholesterol homeostasis Alzheimer’s disease
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fmars.2025.1728727/full
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!