Neuroprotective effect of bexarotene in the SOD1G93A mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive weakness and muscle atrophy related to the loss of upper and lower motor neurons (MNs) without a curative treatment. There is experimental evidence suggesting that retinoids may be involved in ALS pathoge...

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Bibliografiske detaljer

Principais autores:	Javier eRiancho, Maria eRuiz-Soto, Maria T Berciano, José eBerciano, Miguel eLafarga
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2015-07-01
Serier:	Frontiers in Cellular Neuroscience
Fag:	Retinoid X Receptors mouse models proteostasis Amyotrophic Lateral Sclerosis (ALS). Bexarotene hSOD1G93A
Online adgang:	http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00250/full
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