RBM5 induces motor neuron apoptosis in hSOD1G93A-related amyotrophic lateral sclerosis by inhibiting Rac1/AKT pathways

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder distinguished by gradual depletion of motor neurons. RNA binding motif protein 5 (RBM5), an abundantly expressed RNA-binding protein, plays a critical role in the process of cellular death. However, little is known about the r...

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Autori principali:	Xingli Tan, Xiaoli Su, Ying Wang, Weiwei Liang, Di Wang, Di Huo, Hongyong Wang, Yan Qi, Wenmo Zhang, Ling Han, Dongmei Zhang, Ming Wang, Jing Xu, Honglin Feng
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-10-01
Serie:	Brain Research Bulletin
Soggetti:	Amyotrophic lateral sclerosis RBM5 MiRNA Apoptosis
Accesso online:	http://www.sciencedirect.com/science/article/pii/S0361923024001825
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