Mitochondrial-targeted plastoquinone therapy prevents early onset muscle weakness that occurs before atrophy during ovarian cancer

Objective: Muscle loss with cancer causes weakness, worsens quality of life, and predicts reduced overall survival rates. Recently, muscle weakness was identified during early-stage cancer before atrophy develops. This discovery indicates that mechanisms independent of muscle loss must contribute to...

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Үндсэн зохиолчид:	Luca J. Delfinis, Shahrzad Khajehzadehshoushtar, Luke D. Flewwelling, Nathaniel J. Andrews, Madison C. Garibotti, Shivam Gandhi, Aditya N. Brahmbhatt, Brooke A. Morris, Bianca Garlisi, Sylvia Lauks, Caroline Aitken, Leslie Ogilvie, Stavroula Tsitkanou, Jeremy A. Simpson, Nicholas P. Greene, Arthur J. Cheng, Jim Petrik, Christopher G.R. Perry
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2025-09-01
Цуврал:	Molecular Metabolism
Нөхцлүүд:	Ovarian cancer cachexia Mitochondria Skeletal muscle
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2212877825001188
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!