Reprogramming the immunosuppressive tumor microenvironment: exploiting angiogenesis and thrombosis to enhance immunotherapy

This review focuses on the immunosuppressive effects of tumor angiogenesis and coagulation on the tumor microenvironment (TME). We summarize previous research efforts leveraging these observations and targeting these processes to enhance immunotherapy outcomes. Clinical trials have documented improv...

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Главные авторы:	Areez Shafqat, Mohamed H. Omer, Eman Nayaz Ahmed, Ali Mushtaq, Eman Ijaz, Zara Ahmed, Khaled Alkattan, Ahmed Yaqinuddin
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-07-01
Серии:	Frontiers in Immunology
Предметы:	immunotherapy tumor microenvironment angiogenesis thrombosis vascular normalization hypoxia
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1200941/full
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