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Baseline resistance to nucleoside reverse transcriptase inhibitors fails to predict virologic response to combination therapy in children (PACTG 338)

<p>Abstract</p> <p>Background</p> <p>The association between baseline drug resistance mutations and subsequent increase in viral failure has not been established for HIV-infected children. We evaluated drug resistance mutations at 39 codon sites (21 protease inhibitor (PI) resistant codons and 18 nu...

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Autori principali: McIntosh Kenneth, Yogev Ram, Mofenson Lynne M, Wiznia Andrew A, Hu Chengcheng, Petch Leslie A, Kovacs Andrea, Fiscus Susan A, Pelton Stephen I, Napravnik Sonia, Stanley Kenneth, Nachman Sharon A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2007-02-01
Serie:AIDS Research and Therapy
Accesso online:http://www.aidsrestherapy.com/content/4/1/2
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