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Paeoniflorin inhibits angiogenesis in multiple myeloma by decreasing the MEF2A level to downregulate the expression of lncRNA MALAT1 within exosomes

Abstract Angiogenesis is a pivotal mechanism driving tumor proliferation, and the epigenetic regulation of angiogenesis represents a cutting-edge area of current research in multiple myeloma (MM). High-throughput sequencing was carried out to detect the cargos of exosomes from clinical serum and U26...

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Main Authors: Jiaqi Fu, Junqiang Wang, Jie Zhang, Runjie Sun, Manya Yu, Muyun Wu, Xing Cui
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2025-12-01
Series:Scientific Reports
Subjects:
MALAT1
MEF2A
Exosome
Paeoniflorin
Angiogenesis
Multiple myeloma
Online Access:https://doi.org/10.1038/s41598-025-30101-6
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