miR-124-3p sabotages lncRNA MALAT1 stability to repress chondrocyte pyroptosis and relieve cartilage injury in osteoarthritis

Abstract Background Osteoarthritis (OA) is a prevalent inflammatory joint disorder. microRNAs (miRNAs) are increasingly involved in OA. Aim Our study is proposed to clarify the role of miR-124-3p in chondrocyte pyroptosis and cartilage injury in OA. Methods OA mouse model was established via the tre...

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Bibliografske podrobnosti

Principais autores:	Rigbat Rozi, Yubo Zhou, Kai Rong, Pingbo Chen
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2022-10-01
Serija:	Journal of Orthopaedic Surgery and Research
Teme:	Osteoarthritis microRNA-124-3p LncRNA MALAT1 Pyroptosis LncRNA stability Chondrocytes
Online dostop:	https://doi.org/10.1186/s13018-022-03334-8
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