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Actomyosin rings constrain CD40 mobility to organize the dendritic cell immunological synapse

Abstract Background The interaction between dendritic cell CD40 and T cell CD40L is critical for dendritic cell licensing and the initiation of adaptive immunity. The spatial organization of CD40 on the dendritic cell surface is thought to dictate its signaling output, yet the underlying mechanisms...

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Auteurs principaux: Camille D. Clamagirand, Eliane Mallet, Daniel J. Nieves, Christoph Ratswohl, Dylan M. Owen, Jérémie Rossy
Format: Artigo
Langue:Inglês
Publié: BMC 2026-04-01
Collection:Cell Communication and Signaling
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Accès en ligne:https://doi.org/10.1186/s12964-026-02816-0
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