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Intact lymph node homing and CD8+ T-cell priming abilities of Sprouty2-deficient dendritic cells

Sprouty2 (Spry2) acts as a modulator of the MAPK-ERK signaling pathway by exerting both positive and negative regulation in a highly context- and cell type-specific manner. While its role in controlling the migration of non-immune cells in growth factor-dependent contexts is well established and con...

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Principais autores: Nadine Anslinger, Guerric P. B. Samson, Vladimir Purvanov, Michael Basler, Daniel F. Legler
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2026-03-01
Serija:Frontiers in Immunology
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Online dostop:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1761675/full
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