In Silico Design and Verification of LAMP-BDNF Chimeric Protein for Presentation of BDNF on the Surface of Exosomes for Drug Delivery Through Blood-Brain Barrier

Background and purpose: The mature form of brain-derived neurotrophic factor (BDNF) binds to BDNF/NT-3 growth factors receptor (Trk-B). This binding leads to activation of Ras–MAPK pathway which is integrated with cell growth and proliferation. The BDNF deficiency is correlated with various diseases...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Saeed Khalili, Seyedeh Farzaneh Mahdavian, Niloufar Ahmadifard, Reza Valadan, Naghi Shahabi Majd, Hosein Ranjbaran, Mohammad Reza Mahdavi, Atena Sharif Razavi, Shabanali Khodashenas
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Mazandaran University of Medical Sciences 2022-12-01
سلاسل:	Journal of Mazandaran University of Medical Sciences
الموضوعات:	exosomes bdnf trk-b lamp2 drug delivery
الوصول للمادة أونلاين:	http://jmums.mazums.ac.ir/article-1-17695-en.html
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!