High-dose third-generation EGFR-TKIs combined with intrathecal pemetrexed in advanced EGFR-mutant NSCLC with leptomeningeal metastases following EGFR-TKI therapy

Abstract Background Leptomeningeal metastasis in EGFR-mutant (EGFRm) non-small-cell lung cancer (NSCLC) is a severe complication particularly prevalent in patients who have previously been treated with EGFR-tyrosine kinase inhibitors (EGFR-TKIs). However, an optimal treatment strategy for dealing wi...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Shugui Wu, Zhengang Qiu, Huaqiu Shi, Wei Yu, Linfang Liu, Longqiu Wu, Wenjuan Zhong
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2025-05-01
Saila:	BMC Cancer
Gaiak:	Leptomeningeal metastasis Intrathecal chemotherapy Pemetrexed Non-small-cell lung cancer EGFR-tyrosine kinase inhibitors
Sarrera elektronikoa:	https://doi.org/10.1186/s12885-025-14337-z
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!