Incubation of social deficit during morphine abstinence in male mice using a novel unbiased and automatized method

IntroductionOpioid use disorder (OUD) is a chronic relapsing condition caused by prolonged opioid exposure, which triggers adaptive changes in the brain. These changes make it challenging to control or abstain from consuming, and significantly increase the risk of relapse. While the physical symptom...

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Autors principals:	Victor P. Mathis, Gabriele Giua, Nicolas Torquet, Christophe Mittelhaeuser, Raphael Bour, Brigitte L. Kieffer, Fabrice Riet, Emmanuel Darcq
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-10-01
Col·lecció:	Frontiers in Behavioral Neuroscience
Matèries:	opioid protracted abstinence social deficits withdrawal morphine
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fnbeh.2025.1697469/full
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