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Anxiolytic/Sedative Effect of Monoterpene (–)-Borneol in Mice and In Silico Molecular Interaction with GABA<sub>A</sub> Receptor

Anxiety is a normal behavioral component. When it is too frequent or appears in inappropriate contexts, it can be considered pathological. Benzodiazepines (BDZs) are drugs with clinical success in anxiety treatment. BDZs act as allosteric modulators of the γ- aminobutyric acid A receptor (GABA<sub>A...

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Principais autores: Maurício Pires de Moura do Amaral, Marcelo Pereira da Silva Junior, Francisco das Chagas Alves Lima, Stanley Juan Chavez Gutierrez, Daniel Dias Rufino Arcanjo, Rita de Cássia Meneses Oliveira
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-01-01
Serier:Future Pharmacology
Fag:
anxiety
sedation
GABA<sub>A</sub>R
monoterpene
(–)-borneol
molecular docking
Online adgang:https://www.mdpi.com/2673-9879/3/1/9
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