DNA Polymerase IV dinB Favors the Adaptive Fitness of mcr‐carrying Bacteria Through a Negative Feedback Regulatory Mechanism

Abstract The plasmid‐borne resistance gene mcr drastically undermines the effectiveness of colistin, posing a substantial threat to public health. Although several key plasmid elements that balance mcr‐1 persistence and bacterial growth are identified, the regulatory interactions between mcr‐1 and h...

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Detalhes bibliográficos

Principais autores:	Haijie Zhang, Xia Xiao, Chenlong Wang, Yurong Zhao, Bo Chen, Xinyuan Ji, Lina Gu, Jie Wang, Zhiqiang Wang, Yuan Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-03-01
Colecção:	Advanced Science
Assuntos:	bacteria colistin resistance dinB fitness cost mcr expression
Acesso em linha:	https://doi.org/10.1002/advs.202411994
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