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Combination of astragalus polysaccharide with Diosbulbin B exerts an enhanced antitumor effect in BRAF mut papillary thyroid cancer with decreased liver toxicity

Abstract Background Diosbulbin B (DB) is a traditional Chinese medicine used for thyroid cancer treatment, but always brings severe liver injury. In the current study, we investigated the role of astragalus polysaccharide (APS) in DB-induced hepatotoxicity and their anti-tumor effect on BRAF mut pap...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Shuai Xu, Qi Liang, Hang Li, Hai Zhou, Zhenyuan Xu, Yanjun Yan, Yue Zhang, Renqun Ye, Xujun You
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2025-07-01
Rangatū:Cancer Cell International
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12935-025-03853-4
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