Axon initial segment damage and hyperexcitability in a mutant mouse with increased calpain-dependent cleavage of αII-Spectrin
The cytoskeleton is essential for maintaining the structural integrity of axons and the axon initial segment (AIS), a specialized domain located at the axon shaft that plays a critical role in regulating neuronal excitability. Among cytoskeletal components, spectrins are key structural proteins that...
שמור ב:
| Principais autores: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Elsevier
2025-12-01
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| סדרה: | Neurobiology of Disease |
| נושאים: | |
| גישה מקוונת: | http://www.sciencedirect.com/science/article/pii/S0969996125003730 |
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