Axon initial segment damage and hyperexcitability in a mutant mouse with increased calpain-dependent cleavage of αII-Spectrin
The cytoskeleton is essential for maintaining the structural integrity of axons and the axon initial segment (AIS), a specialized domain located at the axon shaft that plays a critical role in regulating neuronal excitability. Among cytoskeletal components, spectrins are key structural proteins that...
Gardado en:
| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2025-12-01
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| Series: | Neurobiology of Disease |
| Assuntos: | |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S0969996125003730 |
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