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Optimization of Culture Media and Feeding Strategy for High Titer Production of an Adenoviral Vector in HEK 293 Fed-Batch Culture

Adenoviruses are efficient and safe vectors for delivering target antigens and adenovirus-based vaccines have been used against a wide variety of pathogens, including tuberculosis and COVID-19. Cost-effective and scalable biomanufacturing processes are critical for the commercialization of adenoviru...

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Principais autores: Chun Fang Shen, Anja Rodenbrock, Stephane Lanthier, Elodie Burney, Martin Loignon
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2024-05-01
Serija:Vaccines
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Online dostop:https://www.mdpi.com/2076-393X/12/5/524
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