iMATCH: an integrated modular assembly system for therapeutic combination high-capacity adenovirus gene therapy

Adenovirus-mediated combination gene therapies have shown promising results in vaccination or treating malignant and genetic diseases. Nevertheless, an efficient system for the rapid assembly and incorporation of therapeutic genes into high-capacity adenoviral vectors (HCAdVs) is still missing. In t...

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Detalles Bibliográficos

Principais autores:	Dominik Brücher, Nicole Kirchhammer, Sheena N. Smith, Jatina Schumacher, Nina Schumacher, Jonas Kolibius, Patrick C. Freitag, Markus Schmid, Fabian Weiss, Corina Keller, Melanie Grove, Urs F. Greber, Alfred Zippelius, Andreas Plückthun
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2021-03-01
Series:	Molecular Therapy: Methods & Clinical Development
Assuntos:	high-capacity vectors helper-dependent adenovirus gutless adenovirus gene therapy cancer therapy immunotherapy
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2329050121000024
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