Classification and regulatory interactions of key transcription factors in COVID-19

SARS-CoV-2, the virus responsible for COVID-19, interferes with the host’s transcriptional control systems, triggering widespread disruption of immune regulation and metabolic stability. Key transcription factors (TFs), including AHR, NRF2, NF-κB, IRFs, HIF-1α, PARP, STAT3, ATF3, and PPARγ, play cru...

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Autors principals:	Ndimo Modipane, Saidon Mbambara, Thato Serite, Mike Sathekge, Mankgopo Kgatle
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-09-01
Col·lecció:	Frontiers in Cellular and Infection Microbiology
Matèries:	AHR Nrf2 HIF-1α PPARγ NF-κB IRF
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fcimb.2025.1645333/full
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