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Classification and regulatory interactions of key transcription factors in COVID-19

SARS-CoV-2, the virus responsible for COVID-19, interferes with the host’s transcriptional control systems, triggering widespread disruption of immune regulation and metabolic stability. Key transcription factors (TFs), including AHR, NRF2, NF-κB, IRFs, HIF-1α, PARP, STAT3, ATF3, and PPARγ, play cru...

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Main Authors: Ndimo Modipane, Saidon Mbambara, Thato Serite, Mike Sathekge, Mankgopo Kgatle
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2025-09-01
Series:Frontiers in Cellular and Infection Microbiology
Assuntos:
AHR
IRF
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1645333/full
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