A novel Mcl-1 inhibitor synergizes with venetoclax to induce apoptosis in cancer cells
Abstract Background Evading apoptosis by overexpression of anti-apoptotic Bcl-2 family proteins is a hallmark of cancer cells and the Bcl-2 selective inhibitor venetoclax is widely used in the treatment of hematologic malignancies. Mcl-1, another anti-apoptotic Bcl-2 family member, is recognized as...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2023-01-01
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| Col·lecció: | Molecular Medicine |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1186/s10020-022-00565-7 |
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