Immunogenicity of a bivalent recombinant adenovirus expressing VP1 proteins of bovine norovirus and bovine nebovirus in mice and calves

Abstract Bovine norovirus (BNoV) and bovine nebovirus (BNeV) are emerging pathogens responsible for severe diarrhea in calves worldwide. In this study, we constructed a bivalent recombinant adenovirus vector vaccine, designated rAd5-BNoV + BNeV_VP1 encoding the genes for BNoV-VP1 and BNeV-VP1 based...

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主要な著者:	Taoyun Chen, Jun Chu, Xin Song, Qisheng Yu, Gunan Deng, Jiangyong Zeng, Changqing Yu, Bin Zhang
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-12-01
シリーズ:	BMC Microbiology
主題:	Bovine norovirus Bovine nebovirus Replication-deficient human type 5 adenovirus vector VP1 protein Immune effects
オンライン･アクセス:	https://doi.org/10.1186/s12866-025-04542-y
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