PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates

PRDM16 loss in cardiomyocytes during development causes an atrial and conduction fate shift and distal ventricular conduction system hyperplasia resulting in premature death or cardiac dysfunction. PRDM16 is a transcription factor with histone methyltransferase activity expressed at the earliest sta...

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Bibliografiske detaljer

Principais autores:	Jore Van Wauwe, Alexia Mahy, Sander Craps, Samaneh Ekhteraei-Tousi, Pieter Vrancaert, Hannelore Kemps, Wouter Dheedene, Rosa Doñate Puertas, Sander Trenson, H. Llewelyn Roderick, Manu Beerens, Aernout Luttun
Format:	Artigo
Sprog:	Inglês
Udgivet:	Life Science Alliance LLC 2024-12-01
Serier:	Life Science Alliance
Online adgang:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202402719
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