PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates

PRDM16 loss in cardiomyocytes during development causes an atrial and conduction fate shift and distal ventricular conduction system hyperplasia resulting in premature death or cardiac dysfunction. PRDM16 is a transcription factor with histone methyltransferase activity expressed at the earliest sta...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Jore Van Wauwe, Alexia Mahy, Sander Craps, Samaneh Ekhteraei-Tousi, Pieter Vrancaert, Hannelore Kemps, Wouter Dheedene, Rosa Doñate Puertas, Sander Trenson, H. Llewelyn Roderick, Manu Beerens, Aernout Luttun
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Life Science Alliance LLC 2024-12-01
coleção:	Life Science Alliance
Acesso em linha:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202402719
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!