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Impaired intestinal free fatty acid transport followed by chylomicron malformation, not pancreatic insufficiency, cause metabolic defects in cystic fibrosis

Intestinal disease is one of the earliest manifestations of cystic fibrosis (CF) in children and is closely tied to deficits in growth and nutrition, both of which are directly linked to future mortality. Patients are treated aggressively with pancreatic enzyme replacement therapy and a high-fat die...

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Uloženo v:
Hlavní autoři: Lihong Teng, Nikolaos Dedousis, Aneseh Adeshirlarijaney, Jitendra S. Kanshana, Min Liu, Craig A. Hodges, Alison B. Kohan
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2024-07-01
Edice:Journal of Lipid Research
Témata:
fatty acid transport
cystic fibrosis
intestine
chylomicrons
lipid metabolism
dietary fat
On-line přístup:http://www.sciencedirect.com/science/article/pii/S0022227524000567
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