<i>N</i>-Acylated and <i>N</i>-Alkylated 2-Aminobenzothiazoles Are Novel Agents That Suppress the Generation of Prostaglandin E₂

The quest for novel agents to regulate the generation of prostaglandin E₂ (PGE₂) is of high importance because this eicosanoid is a key player in inflammatory diseases. We synthesized a series of <i>N</i>-acylated and <i>N</i>-alkylated 2-aminobenzothiazoles and related heteroc...

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Autors principals:	Maria A. Theodoropoulou, Anastasia Psarra, Martin Erhardt, Aikaterini Nikolaou, Anna-Dimitra D. Gerogiannopoulou, Dimitra Hadjipavlou-Litina, Daiki Hayashi, Edward A. Dennis, Andrea Huwiler, George Kokotos
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-02-01
Col·lecció:	Biomolecules
Matèries:	<i>N</i>-acylated 2-aminobenzothiazoles <i>N</i>-alkylated 2-aminobenzothiazoles anti-inflammatory agents mesangial cells prostaglandin E<sub>2</sub>
Accés en línia:	https://www.mdpi.com/2218-273X/12/2/267
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