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Small Peptides Able to Suppress Prostaglandin E2 Generation in Renal Mesangial Cells

Peptide drug discovery may play a key role in the identification of novel medicinal agents. Here, we present the development of novel small peptides able to suppress the production of PGE2 in mesangial cells. The new compounds were generated by structural alterations applied on GK115, a novel inhibi...

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Principais autores: Sofia Vasilakaki, Oleksandr Pastukhov, Thomas Mavromoustakos, Andrea Huwiler, George Kokotos
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2018-01-01
Serier:Molecules
Fag:
inhibitors
mesangial cells
peptides
prostaglandin E2
secreted phospholipase A2
Online adgang:http://www.mdpi.com/1420-3049/23/1/158
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