Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity
Abstract Mitochondrial fusion/fission dynamics plays a fundamental role in neuroprotection; however, there is still a severe lack of therapeutic targets for this biological process. Here, we found that the naturally derived small molecule echinacoside (ECH) significantly promotes mitochondrial fusio...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Nature Publishing Group
2021-02-01
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| سلاسل: | Signal Transduction and Targeted Therapy |
| الوصول للمادة أونلاين: | https://doi.org/10.1038/s41392-020-00447-6 |
| الوسوم: |
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