A case report of TBL1XR1-RARB positive pediatric acute promyelocytic leukemia and literature review

BackgroundAcute promyelocytic leukemia (APL) is classically driven by the PML-RARA fusion oncogene and characterized by a maturation arrest of myeloid precursors. Variant APL (vAPL) with alternative RARA rearrangements presents diagnostic and therapeutic challenges.MethodsWe report a novel case of T...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Chunyan Du, Fu Liu, Linlin Huang, Ruxue Zeng, Jiamei Fan, Tao Hu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-08-01
Schriftenreihe:	Frontiers in Oncology
Schlagworte:	TBL1XR1-RARB fusion atypical acute promyelocytic leukemia clinical characteristics immunophenotype treatment
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1566404/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!