A case report of TBL1XR1-RARB positive pediatric acute promyelocytic leukemia and literature review

BackgroundAcute promyelocytic leukemia (APL) is classically driven by the PML-RARA fusion oncogene and characterized by a maturation arrest of myeloid precursors. Variant APL (vAPL) with alternative RARA rearrangements presents diagnostic and therapeutic challenges.MethodsWe report a novel case of T...

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Bibliografiset tiedot

Päätekijät:	Chunyan Du, Fu Liu, Linlin Huang, Ruxue Zeng, Jiamei Fan, Tao Hu
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2025-08-01
Sarja:	Frontiers in Oncology
Aiheet:	TBL1XR1-RARB fusion atypical acute promyelocytic leukemia clinical characteristics immunophenotype treatment
Linkit:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1566404/full
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