Exacerbated lung inflammation following secondary RSV exposure is CD4+ T cell-dependent and is not mitigated in infant BALB/c mice born to PreF-vaccinated dams

Respiratory syncytial virus (RSV) is the leading cause of childhood hospitalizations due to bronchiolitis in children under 5 years of age. Moreover, severe RSV disease requiring hospitalization is associated with the subsequent development of wheezing and asthma. Due to the young age in which viral...

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Principais autores:	Jessica L. Kosanovich, Katherine M. Eichinger, Madeline A. Lipp, Sonal V. Gidwani, Devarshi Brahmbhatt, Mark A. Yondola, Timothy N. Perkins, Kerry M. Empey
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2023-08-01
סדרה:	Frontiers in Immunology
נושאים:	Respiratory syncytial virus maternal immunization type 2 inflammation secondary RSV exposure T cell-mediated pathology
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1206026/full
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