B-cell tumor development in Tet2-deficient mice
Abstract: The TET2 gene encodes an α-ketoglutarate–dependent dioxygenase able to oxidize 5-methylcytosine into 5-hydroxymethylcytosine, which is a step toward active DNA demethylation. TET2 is frequently mutated in myeloid malignancies but also in B- and T-cell malignancies. TET2 somatic mutations a...
-д хадгалсан:
| Үндсэн зохиолчид: | , , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
Elsevier
2018-03-01
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| Цуврал: | Blood Advances |
| Онлайн хандалт: | http://www.sciencedirect.com/science/article/pii/S247395292031065X |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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