pyHiM: a new open-source, multi-platform software package for spatial genomics based on multiplexed DNA-FISH imaging
Abstract Genome-wide ensemble sequencing methods improved our understanding of chromatin organization in eukaryotes but lack the ability to capture single-cell heterogeneity and spatial organization. To overcome these limitations, new imaging-based methods have emerged, giving rise to the field of s...
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| Principais autores: | , , , , , , , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
BMC
2024-02-01
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| 丛编: | Genome Biology |
| 主题: | |
| 在线阅读: | https://doi.org/10.1186/s13059-024-03178-x |
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