pyHiM: a new open-source, multi-platform software package for spatial genomics based on multiplexed DNA-FISH imaging

Abstract Genome-wide ensemble sequencing methods improved our understanding of chromatin organization in eukaryotes but lack the ability to capture single-cell heterogeneity and spatial organization. To overcome these limitations, new imaging-based methods have emerged, giving rise to the field of s...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Xavier Devos, Jean-Bernard Fiche, Marion Bardou, Olivier Messina, Christophe Houbron, Julian Gurgo, Marie Schaeffer, Markus Götz, Thomas Walter, Florian Mueller, Marcelo Nollmann
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-02-01
Serie:	Genome Biology
Soggetti:	Spatial genomics 3D chromatin structure Transcription Imaging Bioimage informatics
Accesso online:	https://doi.org/10.1186/s13059-024-03178-x
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!